Sunday, January 8, 2012

The relationship between cortisol and hair loss


This was a response I wrote to a thread on ************.com.

This is the reason why cortisol levels and hair shedding/loss are intertwined.

Cortisol(Corticosteroids) blocks cellular differentiation.

So, the reason we experience hair loss is because the cortisol response from the DHT sensitivity eventually halts our hair stem cells from differentiating into the hair follicle matrix. At the same time the hair follicle matrix which produces the keratinized portion of the hair, is susceptible as well. Therefore over time as cortisol levels increase and begin to saturate the matrix the hair matrix itself begins to get smaller and thinner, then the matrix is unable to build a thick healthy follicle.

Second, nano lipid encapsulation does actually work very well for large molecule chemicals; > 1000g/mol.

Third, after the cortisol is removed the cellular differentiation is immediately resumed.

Forth, each person has a different threshold for DHT sensitivity and will incur a different cortisol response level. Some people may have a high DHT response that highly increases cortisol while others may have a very low DHT response with very minor cortisol increases. Therefore, some people may need to drop the cortisol by a large margin while other people may need to drop it only slightly.

So, in a true setting; not spectral F7. You would have a pure source of astressin-b encapsulated with nano lipids. Then you would apply that as much as needed to reduce your specific cortisol response to as low as possible.

My feelings on astressin-b are that while it works it may be impractical in the long run as it affects your ACTH levels as well as the corticosteroids.

5 comments:

  1. will your method also affect acth and corticosteroid

    ReplyDelete
  2. PS taken orally has no effect on ACTH. However, combined with DMSO it may.

    ReplyDelete
  3. So let me understand (and sorry for my English): do you think F7 could be useful, unuseful, or...? Would you use it just for a couple of months and then take a break for a while, and then use it again? Would you use it everyday, three times a week...?

    ReplyDelete
  4. Hello,
    i always thought Corticotropin is atress hormon, the mice were manipulated for the test to produce Corticotropin everytime, they were under stress and thats why they lost the hairs. The test should discover how stress will affect your stomach. It is well known that stress and depression lead to hair loss probaply because of Corticotropin? Thats why they injected Astressin-B which is a Corticotropin blocker. It had no affect on the stomach but the mice got their hairs back within some month

    ReplyDelete
  5. Reread the study results. Some of the mice were suffering from galbladder issues. Cortisol is used by many different parts of the body for different functions.

    ReplyDelete