The major side effects when starting were:
- Hyper kinetic gallbladder - overactive bile production in the small intestine
- Hypersomnia - inability to wake up
I believe that my body has now stabilized with the new lower level of cortisol and generally I feel great. I still feel sleepy in the mornings but I no longer have any trouble waking up. My gallbladder is no longer giving me explosive shits after eating food which is wonderful. Keep in mind the diarrhea was only after eating and did not continue through the day which made it manageable. That lasted for about a month and a half.
Some minor side effects that are still ongoing are general stinky head syndrome. The stuff stinks; so I generally try to rinse my head off after it has dried. Also, dandruff which I believe is mostly due to the allantoin. The level of dandruff waxes and wanes. This last batch I made had an excess amount of allantoin in it which has produced more dandruff that normal. The vitamin b-6 gave me headaches the first couple of days after adding it but those have gone away.
If this works and I obtain full regrowth I will likely remove the allantoin as I dont believe it will be needed anymore. And I will also begin testing other methods of transdermal delivery. All my ingredients have a molecular weight of less than 400 g/mol and other delivery systems may work. The DMSO however is such a potent anti-inflammatory that I have hesitant of taking it away completely.
On a side note, I broke my index finger about 10 years ago and it had lost quite a bit of mobility. Interestingly, since starting this treatment I have regained the ability to flex/bend it.
I am beginning to think that the keratolyic effect of allantoin combined with anti-inflammatories allows the body to regenerate instead of repair by loosening keratinized cells at such a rate that the body is able to heal with out going into repair mode.