Wednesday, November 16, 2011

Filaggrin and Hair Shedding

I have added vitamin b6 to my mix after reading this article. Click here to read.

I mentioned in previous post that I was seeing both increased hairs and increased shedding. Also, I pointed out that the hair bulb of the new cells were noticeably smaller. And so I began researching for something to add to my mix that will hopefully abate the hair shedding and increase the hair bulb(follicle matrix) size.

Filaggrin is known as a protein filament that is used to increase strength and structure to cells. Epithelial cells (which the hair matrix is mostly made of) use to filaggrin to bind themselves to keratin.

Vitamin B6 up-regulates mRNA expression of profilaggrin which derives into individual filaggrin proteins. So adding this will hopefully this will help with my hair shedding. I'll update later on if I notice less or more hair shedding.

There are toxicity problems with vitamin b-6 therefore I only add 250mg to my mix. This should result in 4-8 mg per day well below the RDA amount.

Amazon link:
Country Life Coenzyme Active B-6

Also, I reduced the allantoin to 1% because of excess skin peeling. I'll post new pictures soon.

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